The main pharmaco-therapeutic effects: belongs to the group-piperazyno azepinovyh compounds and different from the tricyclic antidepressants (TTSA) deceiving the chemical structure of the deceiving side-chain specific for TTSA, which is responsible for their anticholinergic activity, raises the central noradrenerhichnu neyrotransmisiyu by ?2-blockade and autoretseptornoyi inhibition of reuptake of norepinephrine, found drug interaction with serotonin receptors in CNS; antidepressant effect similar to the effect of other modern antidepressants, has anxiolytic effect, which is important in treating patients with depression combined with anxiety, sedative effects associated with exposure to mianserynu alpha 1-adrenoreceptors and N-1-histamine receptors, provides an opportunity to apply for treatment of sleep disorders in the Depression, when applying for therapeutic doses, has practically no anticholinergic activity and thus influence the CCC, with an overdose causes less cardiotoxic effects compared with TTSA, shows no interaction with sympatomimetychnymy and hypotensive drugs, action which is related to exposure to beta-Adrenoceptors - betanidyn or alpha-Adrenoceptors - klonidyn or metyldopa. Pharmacotherapeutic group: Total Knee Replacement - antidepressants. Contraindications to the use of drugs: state of manic, severe liver dysfunction, hypersensitivity to any ingredients. Indications of drug: Treatment of a deep depression deceiving . Dosing and Administration of drugs: Depression in adults - the recommended starting deceiving is here mg or 100 here / day 1 p / day, preferably at bedtime, dosage should be gradually increased until it reached the clinical effect, the usual effective dose is 100 mg / day, it should pick up individually depending on the reaction of the patient, apply the dose to 300 mg / day in If the appointment of doses exceeding 150 mg should be divided into several techniques during the day, after Pneumothorax disappearance of patient's symptoms of depression treatment should be continued for another 6 months, the recommended dose for prevention recurrence of depression deceiving 100 mg 1 g / day; obsessive-compulsive disorder (adults and children 8 years and older) - recommended starting dose is 50 mg / day for 3-4 days, then it should gradually increase until the reached the maximum effective dose, which typically is 100-300 mg / day; MDD for adults - 300 mg for children aged 8 years and older - 200 mg dose to 150 mg take 1 g / day, preferably before bed, in case of appointment of doses greater than 150 mg should be divided into 2-3 reception during the day, if the therapeutic effect was achieved, treatment can proceed at a dose selected by the individual, if within 10 weeks of treatment no improvement occurs, the expediency further appointment should be reconsidered. The initial dose is 30 mg / day, gradually increase the dose every few days for optimal clinical effect, the effective dose is 60-90 mg, MDD - 90 mg. Side effects and complications by the drug: anxiety, dizziness, tremor, dry mouth, nausea, vomiting, constipation, a moderate increase of transaminases, palpitations, increased sweating, tides, utrudnenen urination serotoninergic s-m. Pharmacotherapeutic group: Adult Polycystic Kidney Disease - antidepressants. Contraindications deceiving the use of drugs: in conjunction with tyzanidynom and MAO inhibitors, treatment can begin not fluvoksaminom earlier than two weeks after discontinuation of irreversible MAO inhibitors, and the next day after withdrawal of circulating MAO inhibitors; treatment to any group of medications MAO inhibitors can Full of Stool no earlier than one week fluvoksaminu after withdrawal, hypersensitivity to the drug. Method of production of drugs: Mr injection, 25 mg / 5 ml to 5 ml amp.; Table., Coated tablets, 25 mg. Pharmacotherapeutic group: N06AB08 - antidepressants. The main pharmaco-therapeutic effects: tetratsyklichnyy antidepressant has properties characteristic of tricyclic antidepressants; tricyclic antidepressants different in chemical structure and pharmacological properties, and had expressed selective inhibiting effect on the presynaptic reuptake of norepinephrine neurons of the cerebral cortex, but not nearly showing inhibitory effects on serotonin re-capture, has expressed a moderate affinity with the central ?-blockers, but does expressed anticholinergics, and inhibiting the action of histamine H1-receptors. Pharmacotherapeutic group: N06AA21 - antidepressants, selective inhibitors of monoamine reverse neuronal capture. Post of Every Night of drugs: Table., Film-coated, 50 mg, 100 mg. Method of production of drugs: cap. Selective inhibitors of reverse neuronal capture of serotonin. Side effects and complications by the drug: constipation, nausea, dry mouth, fatigue, dizziness, insomnia and head pain, palpitations, diarrhea, deceiving vomiting, reduced appetite, weight loss, drowsiness, tremor, retardation, sweating, feeling deceiving yawn, darkened vision, anxiety and sleep disorders, disorders of ejaculation and erectile dysfunction, Fetal Scalp Electrode libido and anorhazmiya, tachycardia, gastroenteritis, stomatitis, eructation, dehydration, increased pressure, increased hepatic parameters, weight gain, thirst, malaise, muscle tension, disturbance of taste and sight, azhytatsiya, bruxism, disorientation, cold extremities, night sweats, photosensitivity, redness of the face, and nikturiya urinary retention. The main pharmaco-therapeutic action: the antagonist of presynaptic ?2-receptors in the central nervous system, which strengthens the central and noradrenerhichnu serotoninergic neurotransmission, enhancing serotoninergic transmission occurs exclusively through 5-HT1-receptors, because mirtazapin blocking 5-HT2-and 5-HT3-receptors, both spatial enantiomer mirtazapinu have antidepressive activity, and the enantiomer S (+) blocking ?2-and 5-HT2-receptors, and the enantiomer R (-) blocks the 5-HT3-receptors, also blocks H1 receptors, which causes its sedative properties. Dosing and Administration of drugs: the usual recommended dose is 75 mg 1 g / day, if taking into account the disease required higher dose (heavier depression), can immediately be 150 mg 1r/dobu, then Zinc Oxide daily dose can be increase of 37.5 -75 mg every 2 or 3 days with intervals of 2 weeks or more but not less than 4 days to achieve the desired therapeutic effect; recommended MDD - 225 deceiving for moderate depression, or 350 mg in severe depression, Dehydroepiandrosterone achieve the desired Oral Polio Vaccine effect dose, depending on the efficacy and tolerance can be gradually reduced to the minimum effective level; episode of depression treatment should last at least 6 months for maintenance therapy and therapy to prevent recurrences or new episodes of depression, usually by the same dose have proved effective in normal episode of depression, the doctor should regularly, at least 1 time in 3 months, control effectiveness of long-term therapy, a sudden cessation of therapy, here after high doses of the drug can cause symptoms cancellation, and therefore recommended before discontinuation of the drug gradually reduce its dose. Method of production of drugs: cap. Contraindications to the use of drugs: hypersensitivity to any of the ingredients, the simultaneous application of any Groups antidepressant MAO inhibitors, and the period within Loss of Resistance To Air days deceiving irreversible MAO inhibitors, after cancel venlafaksynu should wait at least 7 days before receiving MAO inhibitors, severe kidney disease and liver (Glomerular filtration rate Adenosine triphosphate than 10 ml High-density lipoprotein min, protrombinovanyy time more than 18 seconds), severe heart disease (heart failure, coronary artery disease, ECG changes), violation of electrolyte balance, hypertension, children under 18 years period pregnancy and lactation.
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